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Magnetic Resonance Guided Focused Ultrasound (MRgFUS)

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Magnetic resonance guided focused ultrasound (MRgFUS) is a non-invasive therapeutic modality for neurodegenerative diseases that allows real-time imaging of targeted regions. However, MR image quality is poor and severely limits the technology due to the use of the body coil for focal targeting. Acoustic simulations demonstrated an acoustic transparency (signal loss <1%) of an ultra-flexible, ultra-thin, acoustically transparent, 8-channel receive coil that conforms to the shape of the head when used for thalamic sonication. In vivo results showed increase of the SNR over the body coil by a factor of 7.3 and 7.6 in a brain image with and without the presence of the transducer, respectively.

 

Video presentation of this work published at the ISMRM 2021 can be viewed here:

File 4263-saniour.mp4

Video presentation of this work published at the ISMRM 2022 can be viewed here:

File 1376-saniour.mp4

File 1095-saniour.mp4

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